At L.E.M laboratory, we perform thousands of tests every month for the early detection of changes in the cervix - Thinprep tests as well as a test to detect the presence of the human papilloma virus (HPV). Today, the health funds in Israel have switched to the HPV test as the initial test for the early detection of cervical cancer. In the event that the presence of one of the 14 strains of the virus that are considered disease-causing agents is detected, the sample will also undergo a Thinprep test.

Thinprep Liquid base cytology

Thinprep is an advanced test based on the conventional Pap test. The doctor takes a swab from the cervix and puts the sample into a jar with a preservative liquid.

The sample is filtered, and the cells are analyzed by experienced cytoscreeners and pathologists. The advantage of a Thinprep is that there is maximum preservation of the cells in the sample, a minimum of additional elements that may interfere, and the possibility of creating an even and clean sample. Another advantage of a Thinprep test is that when there is suspicion of dysplasia, cell changes that may become pre-cancerous cells, the same material can be used to perform an HPV test.

We have collected for you some questions about Thinprep test:

What is an early detection test for cervical cancer (Thinprep and HPV)?

A cervical smear is a routine test performed by a gynecologist to check the condition of the cells in the cervix. During the test, a tiny sample of cells is taken from the cervix - the lower part of the uterus that connects to the vagina, by a swab. This sample is sent to the laboratory and undergoes a preliminary diagnosis to detect the presence of HPV, the human papilloma virus. In the event that one of the dangerous strains is present, the sample will be sent for further investigation with a Thinprep test - the cervical cells in the sample are tested in the laboratory in order to detect abnormal changes. If such a condition is detected, the doctor may recommend additional tests. It is not a biopsy or an invasive and painful process. It's a simple, potentially life-saving process.

When is it recommended to do a cervical examination?

After having sexual intercourse, or when you turn 21 (whichever comes first). If the HPV test is ok, according to the Ministry of Health, it is recommended to perform the next test after 5 years. This is to the extent that the personal relationship has not changed.

It is important to remember, there are actions that may interfere with the effectiveness of the test:

  • If there is a lot of vaginal discharge, or bleeding or residual bleeding.
  • Having sex 48 hours before the test.
  • Using candles or vaginal ointments before the test.
  • Usually, the tests are performed during ovulation, between 10 and 20 days after the first day of menstruation.

What does an abnormal pap test (cervical surface) mean?

An abnormal Pap smear shows that there are unhealthy changes in the cells. These cells may develop into precancerous cells and cancerous cells.

If there is a suspicion of the presence of a lesion, a cluster of cells, the gynecologist may perform a colposcopy, a test in which a tiny camera is used to see the cervix. In case there is a lesion, it will be removed, usually with the help of a tiny invasive instrument. In cases where there are tumors that require more complex treatment, or cancerous tumors in the cervix, surgery may be performed to remove the tumor along with supportive treatment. It is important to continue the treatment according to the doctors instructions.

Clinics and Gyneocologists contact us for more information: Tel.08-9380770, Fax.08-9389783, E-mail:

Not all changes in the cells indicate cancer. In some cases, the cells will revert to normal after some time, but it is very important to perform tests to eliminate the possibility of cancer.

Go to a doctor you trust! If you feel that something is still wrong, don't ignore it, go for treatment. Early detection saves lives.